Drug-resistant tuberculosis in the 1990s

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Drug-resistant tuberculosis in the 1990s.

There has been an upsurge of tuberculosis in many parts of the world in the past decade. The high rates of drug-resistant tuberculosis currently reported in many countries are alarming. The most catastrophic phenomenon is the emergence of multidrug-resistant strains of Mycobacterium tuberculosis. These organisms have caused epidemic outbreaks in nosocomial and health-care settings in the USA an...

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Extensively drug-resistant (XDR) tuberculosis is defined as disease caused by Mycobacterium tuberculosis with resistance to at least isoniazid and rifampicin, any fluoroquinolone, and at least one of three injectable second-line drugs (amikacin, capreomycin, or kanamycin). The definition has applicable clinical value and has allowed for more uniform surveillance in varied international settings...

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Drug Resistant Tuberculosis

Drug resistant tuberculosis (DRTB) has hit the tuberculosis control programs like a thunderbolt. It has challenged all the aspects of tuberculosis management, from diagnosis till prognosis. India has had a major contribution in DR TB worldwide, with Mumbai city being the niche for DRTB strains. DRTB has emerged distinctly as a “Creation of mankind” than solely as a “Weapon of God” to curtail th...

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Africa has the highest incidence rate per capita of tuberculosis, although the rate varies among the African countries from 17.8% in Cameroon to 70% in Botswana, Zambia, and Zimbabwe. Nevertheless, the levels of drug resistance are relatively low, compared to countries like Russia and Estonia. Because treatment of MDR TB is beyond the reach of most African countries, prevention of the developme...

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 1995

ISSN: 0000-0000,0903-1936

DOI: 10.1183/09031936.95.08071184